Ozone is effectively used as an antibacterial agent to treat oral infections caused by Actinomyces naeslundii, Lactobacilli casei and Streptococcus mutans. Exposure to ozone gas for approximately 60 seconds exhibits 99.9 % killing efficiency but exposure of 10 seconds to 30 seconds was proved effective to kill significant number of bacteria.(
How does Ozone Therapy work on Dental Caries, Physiology and Biochemistry
When ozone enters the system it reacts with biomolecules (PUFA, antioxidants) present in the plasma, the reaction yields hydrogen peroxide (among other possible ROS) and lipid oxidation products (LOPS). ϖ The sudden rise in plasma concentration of hydrogen peroxide generates a gradient, which causes its rapid transfer into blood cells where, in a few seconds, it activates several biochemical processes and simultaneously undergoes reduction to water by the efficient intracellular antioxidant system of the body.
